...And maybe in the area in and between Union Square and the Metreon, new Transbay and Piano Towers, and Pier 39. Actually, I think Pier 39 already has a video board.
I've stayed in hotels in China where they had rather large, bright and elaborate animated flashing lights on the buildings outside my windows. I thought they would bother me a night when I went to bed, but with the right kind of dark curtains, they didn't - same thing in Las Vegas. Again, San Francisco is different. I'm not sure if people would accept it here either, even if they did have the right kind of curtains. This new Mission Bay project, seems like it might be a good place for some animated signage though.