San Francisco, originally named Yerba Buena, eventually adopted the name of its mission church, Mission San Francisco de Asis.
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A . . . group of soldiers, . . . accompanied by settlers, arrived in June 1776, led by the Spanish explorer Juan Bautista De Anza (having trekked up to central California from the Santa Cruz Valley of southern Arizona and northern Mexico). One of De Anza's officers, José Joaquín Moraga, was given the task of building a Spanish mission, Mission San Francisco de Asís, and a military fort, the Presidio of San Francisco. Moraga chose a location approximately halfway between the two sites to build housing for the workers, which became known as Yerba Buena. A supply ship arrived about two months later and the settlers began building.
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https://en.wikipedia.org/wiki/Yerba_Buena,_California
Later, the church was subsumed into the string of missions being established up and down the California coast by Father Junipero Serra.
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Mission San Francisco de Asís is the 6th mission established under Father Serra and one of the most visited due to its location in San Francisco. The mission itself was completed in 1791, and it is one of the oldest intact missions, having survived many earthquakes to be still standing today:
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https://californiathroughmylens.com/...cisco-de-asis/